Effect of QSKL on MAPK and RhoA Pathways in a Rat Model of Heart Failure

Figure 5

Effects of QSKL on collagen deposition (). Collagen was stained blue by Masson staining. When observed under the magnification of 200x, (a) shows that there was little deposition of collagen among cardiac cells. (b) showed that there was extensive deposition of collagens in the model group. (c) and (d) showed that collagens were reduced in QSKL and fosinopril groups as compared with those in the model group. Compared with sham group, the CVF values in the model group were upregulated, and QSKL could decrease the CVF value compared with model group (, , other groups versus model group).