Efficacy of Topical Compound Danxiong Granules for Treatment of Dermatologic Toxicities Induced by Targeted Anticancer Therapy: A Randomized, Double-Blind, Placebo-Controlled Trial

Figure 2

Three representative patients before and after treatment. (a) Acneiform eruption associated with Erlotinib in a patient with lung cancer. Before treatment (left), the face displayed swelling, itching, pain, purulent heads, and hemorrhage (Grade III). After 10 days of topical washes with CDG (right), the rash nearly healed. (b) Paronychia associated with Erlotinib in a patient with lung cancer. Before treatment (left), the nail exhibited pain, redness, and swelling (Grade III). After 10 days of topical washes with CDG (right), the tissues surrounding the nail recovered. (c) Hand-foot skin reaction associated with Sorafenib in a patient with hepatocellular carcinoma. Before treatment (left), skin areas on both hand and foot displayed redness, swelling, foaming, bleeding blister, and pain (Grade III). After 10 days of topical washes with CDG (right), the lesions were nearly healed.

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