Evidence-Based Complementary and Alternative Medicine / 2017 / Article / Tab 1

Research Article

Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia alpinia, with Human Monoamine Oxidase-A and Oxidase-B

Table 1

Inhibition (IC50 values) of recombinant human MAO-A and MAO-B by R. alpinia extract and isolated compounds 1

SamplesMonoamine oxidase-A
IC50 (µM)
Monoamine oxidase-B
IC50 (µM)
Index MAO-A/B

Renealmia alpinia dichloromethane extract2.201
Pinostrobin, 10.524
4′-Methyl ether sakuranetin, 2>100
Sakuranetin, 31.246
Pinostrobin chalcone, 40.610
Yashabushidiol A, 5>100
Desmethoxyyangonin, 615.040
Phenelzine1.566
Clorgyline
Deprenyl

IC50 values computed from the dose response inhibition curves are Mean ± SD of triplicate observations. .

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