Table of Contents Author Guidelines Submit a Manuscript
Corrigendum

A corrigendum for this article has been published. To view the corrigendum, please click here.

Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 4024721, 6 pages
https://doi.org/10.1155/2017/4024721
Research Article

Antioxidant Activity of a Geopropolis from Northeast Brazil: Chemical Characterization and Likely Botanical Origin

1Departamento de Ciências Animais, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil
2Departamento de Botânica, Instituto de Biociências, Universidade de São Paulo, São Paulo, SP, Brazil
3Universidade Federal de São Paulo, São Paulo, SP, Brazil

Correspondence should be addressed to Antonio Salatino; rb.psu.bi@nitalasa

Received 30 May 2017; Revised 27 September 2017; Accepted 8 October 2017; Published 31 October 2017

Academic Editor: Kuttulebbai N. S. Sirajudeen

Copyright © 2017 Joselena M. Ferreira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. A. Heard, “The role of stingless bees in crop pollination,” Annual Review of Entomology, vol. 44, pp. 183–206, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. R. P. Dutra, B. V. D. Abreu, M. S. Cunha et al., “Phenolic acids, hydrolyzable tannins, and antioxidant activity of geopropolis from the stingless bee Melipona fasciculata smith,” Journal of Agricultural and Food Chemistry, vol. 62, no. 12, pp. 2549–2557, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. R. P. Dutra, A. M. C. Nogueira, R. R. D. O. Marques, M. C. P. Costa, and M. N. S. Ribeiro, “Pharmacognostic evaluation of geopropolis of Melipona fasciculata Smith from Baixada Maranhense, Brazil,” Revista Brasileira de Farmacognosia, vol. 18, no. 4, pp. 557–562, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. V. Bankova, “Chemical diversity of propolis and the problem of standardization,” Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 114–117, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Huang, C.-P. Zhang, K. Wang, G. Q. Li, and F.-L. Hu, “Recent advances in the chemical composition of propolis,” Molecules, vol. 19, no. 12, pp. 19610–19632, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Silva-Carvalho, F. Baltazar, and C. Almeida-Aguiar, “Propolis: a complex natural product with a plethora of biological activities that can be explored for drug development,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 206439, 29 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  7. M. J. A. M. Araújo, M. C. Búfalo, B. J. Conti et al., “The chemical composition and pharmacological activities of geopropolis produced by Melipona fasciculata Smith in northeast Brazil,” Journal of Molecular Pathophysiology, vol. 4, no. 1, pp. 12–20, 2015. View at Publisher · View at Google Scholar
  8. M. G. Da Cunha, P. L. Rosalen, M. Franchin et al., “Antiproliferative constituents of geopropolis from the bee melipona scutellaris,” Planta Medica, vol. 82, no. 3, pp. 190–194, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. M. O. Freitas, F. A. F. Ponte, M. A. S. Lima, and E. R. Silveira, “Flavonoids and triterpenes from the nest of the stingless bee Trigona spinipes,” Journal of the Brazilian Chemical Society, vol. 19, no. 3, pp. 532–535, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. M. A. Sanches, A. M. S. Pereira, and J. E. Serrão, “Pharmacological actions of extracts of propolis of stingless bees (Meliponini),” Journal of Apicultural Research, vol. 56, no. 1, pp. 50–57, 2017. View at Publisher · View at Google Scholar · View at Scopus
  11. P. M. Kustiawan, S. Puthong, E. T. Arung, and C. Chanchao, “In vitro cytotoxicity of Indonesian stingless bee products against human cancer cell lines,” Asian Pacific Journal of Tropical Biomedicine, vol. 4, no. 7, pp. 549–556, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. S. Alves De Souza, C. A. Camara, E. Monica Sarmento Da Silva, and T. M. S. Silva, “Composition and antioxidant activity of geopropolis collected by Melipona subnitida (jandaíra) bees,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 801383, 5 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. M. G. da Cunha, M. Franchin, L. C. D. Galvão et al., “Antimicrobial and antiproliferative activities of stingless bee Melipona scutellaris geopropolis,” BMC Complementary and Alternative Medicine, vol. 13, article 23, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. E. C. C. da Silva, M. P. Muniz, R. D. C. S. Nunomura, S. M. Nunomura, and G. A. C. Zilse, “Phenolic constituents and antioxidant activity of geopropolis from two species of amazonian stingless bees,” Química Nova, vol. 36, no. 5, pp. 628–633, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. J. F. Campos, U. P. dos Santos, L. F. B. Macorini et al., “Antimicrobial, antioxidant and cytotoxic activities of propolis from Melipona orbignyi (Hymenoptera, Apidae),” Food and Chemical Toxicology, vol. 65, no. 1, pp. 374–380, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. G. R. Coelho, R. Z. Mendonça, K. D. Vilar et al., “Antiviral action of hydromethanolic extract of geopropolis from Scaptotrigona postica against antiherpes simplex virus (HSV-1),” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 296086, 10 pages, 2015. View at Publisher · View at Google Scholar
  17. C. F. Massaro, M. Katouli, T. Grkovic et al., “Anti-staphylococcal activity of C-methyl flavanones from propolis of Australian stingless bees (Tetragonula carbonaria) and fruit resins of Corymbia torelliana (Myrtaceae),” Fitoterapia, vol. 95, no. 1, pp. 247–257, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. J. M. Ferreira, C. C. Fernandes-Silva, A. Salatino, G. Negri, and D. Message, “New propolis type from north-east Brazil: Chemical composition, antioxidant activity and botanical origin,” Journal of the Science of Food and Agriculture, 2017. View at Publisher · View at Google Scholar · View at Scopus
  19. R. G. Woisky and A. Salatino, “Analysis of propolis: some parameters and procedures for chemical quality control,” Journal of Apicultural Research, vol. 37, no. 2, pp. 99–105, 1998. View at Publisher · View at Google Scholar · View at Scopus
  20. “TRPIQ: Regulamento Técnico para Fixação de Identidade e Qualidade de Própolis,” Portaria n. 3, Instrução Normativa n.3, Ministério da Agricultura, Pecuária e Abastecimento, Brasília, 2001, http://www.engetecno.com.br/port/legislacao/mel_propolis.htm.
  21. A. A. Righi, T. R. Alves, G. Negri, L. M. Marques, H. Breyer, and A. Salatino, “Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities,” Journal of the Science of Food and Agriculture, vol. 91, no. 13, pp. 2363–2370, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. B. Abad-García, L. A. Berrueta, S. Garmón-Lobato, B. Gallo, and F. Vicente, “A general analytical strategy for the characterization of phenolic compounds in fruit juices by high-performance liquid chromatography with diode array detection coupled to electrospray ionization and triple quadrupole mass spectrometry,” Journal of Chromatography A, vol. 1216, no. 28, pp. 5398–5415, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. B. Portet, N. Fabre, R. Rozenberg, J.-L. Habib-Jiwan, C. Moulis, and J. Quetin-Leclercq, “Analysis of minor flavonoids in Piper hostmannianum var. berbicense using liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometry,” Journal of Chromatography A, vol. 1210, no. 1, pp. 45–54, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. C. Engels, D. Gräter, P. Esquivel, V. M. Jiménez, M. G. Gänzle, and A. Schieber, “Characterization of phenolic compounds in jocote (Spondias purpurea L.) peels by ultra high-performance liquid chromatography/electrospray ionization mass spectrometry,” Food Research International, vol. 46, no. 2, pp. 557–562, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. J.-Y. Zhang, N. Li, Y.-Y. Che et al., “Characterization of seventy polymethoxylated flavonoids (PMFs) in the leaves of Murraya paniculata by on-line high-performance liquid chromatography coupled to photodiode array detection and electrospray tandem mass spectrometry,” Journal of Pharmaceutical and Biomedical Analysis, vol. 56, no. 5, pp. 950–961, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. M. G. Miguel, S. Nunes, S. A. Dandlen, A. M. Cavaco, and M. D. Antunes, “Phenols, flavonoids and antioxidant activity of aqueous and methanolic extracts of propolis (Apis mellifera L.) from Algarve, South Portugal,” Food Science and Technology, vol. 34, no. 1, pp. 16–23, 2014. View at Publisher · View at Google Scholar · View at Scopus
  27. A. Daugsch, C. S. Moraes, P. Fort, and Y. K. Park, “Brazilian red propolis—chemical composition and botanical origin,” Evidence-Based Complementary and Alternative Medicine, vol. 5, no. 4, pp. 435–441, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. B. B. Silva, P. L. Rosalen, J. A. Cury et al., “Chemical composition and botanical origin of red propolis, a new type of Brazilian propolis,” Evidence-Based Complementary and Alternative Medicine, vol. 5, no. 3, pp. 313–316, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. Z. Rozmer and P. Perjési, “Naturally occurring chalcones and their biological activities,” Phytochemistry Reviews, 2014. View at Publisher · View at Google Scholar
  30. J. B. Silva, K. M. Costa, W. A. Coelho et al., “Quantificação de fenóis, flavonoides totais e atividades farmacológicas de geoprópolis de Plebeia aff. Flavocincta do Rio Grande do Norte,” Pesquisa Veterinária Brasileira, vol. 36, no. 9, pp. 874–880, 2016. View at Publisher · View at Google Scholar
  31. A. Salatino and M. L. F. Salatino, “Why do honeybees exploit so few plant species as propolis sources?” MOJ Food Processing & Technology, vol. 4, no. 5, 3 pages, 2017. View at Google Scholar
  32. S. Kumar and A. K. Pandey, “Chemistry and biological activities of flavonoids: an overview,” The Scientific World Journal, vol. 2013, Article ID 162750, 16 pages, 2013. View at Publisher · View at Google Scholar
  33. V. Georgiev, A. Ananga, and V. Tsolova, “Recent advances and uses of grape flavonoids as nutraceuticals,” Nutrients, vol. 6, no. 1, pp. 391–415, 2014. View at Publisher · View at Google Scholar · View at Scopus
  34. M. D. Awouafack, P. Tane, M. Spiteller, and J. N. Eloff, “Eriosema (Fabaceae) species represent a rich source of flavonoids with interesting pharmacological activities,” Natural Product Communications (NPC), vol. 10, no. 7, pp. 1325–1330, 2015. View at Google Scholar · View at Scopus
  35. N. K. Sahu, S. S. Balbhadra, J. Choudhary, and D. V. Kohli, “Exploring pharmacological significance of chalcone scaffold: a review,” Current Medicinal Chemistry, vol. 19, no. 2, pp. 209–225, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. P. Singh, A. Anand, and V. Kumar, “Recent developments in biological activities of chalcones: A mini review,” European Journal of Medicinal Chemistry, vol. 85, pp. 758–777, 2014. View at Publisher · View at Google Scholar · View at Scopus