Antidiarrheal Activity of Dissotis multiflora (Sm) Triana (Melastomataceae) Leaf Extract in Wistar Rats and Subacute Toxicity Evaluation

Figure 4

Histological section of kidney tissue (section stained with H&E, ×400). (A) Control with normal urinary room and glomerulus. (B) Kidney of rats treated at the dose of 222.84 mg/kg of D. multiflora with normal aspect without mesangial expansion. (C) Kidney of rats treated at the dose of 445.68 mg/kg of D. multiflora with mesangial expansion and urinary room presenting some alterations. (a) = male; (b) = female; MEGl = mesangial expansion of glomerulus; UR = urinary room; Gl = glomerulus; H&E: Haematoxylin-Eosin.

(a)

(b)