Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway

<div>Curcumin treatments induce AKT pathway in Hep3B cells. (a) Western blot analysis for AKT activation after curcumin treatments. (b) Western blot analysis for FOXO protein localization after curcumin treatments in Hep3B cells. The concentration of curcumin used in the experiments was 50 <i>μ</i>M. The data are representative of triplicate experiments.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway 