Yangyin Runchang Decoction Improves Intestinal Motility in Mice with Atropine/Diphenoxylate-Induced Slow-Transit Constipation

Figure 4

Effects of YRD on SCF and c-kit expression in mice with atropine/diphenoxylate-induced STC. (a) A lower serum SCF level was observed in the MC group ( indicates   when compared to the NC group). After treatment with YRD for 2 weeks, higher serum levels of SCF were detected in both the L-YRD and H-YRD groups ( indicates  ). (b) A lower protein expression of SCF was observed in the MC group ( indicates   when compared to the NC group), and this change was ameliorated in both the L-YRD and H-YRD groups. Similar results were obtained for SCF mRNA expression. (c) A lower protein expression of c-kit was observed in the MC group ( indicates   when compared to the NC group); however, this change was ameliorated in the L-YRD and H-YRD groups ( indicates  ). Similar results were obtained for c-kit mRNA expression.

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