Glucose Metabolic Changes in the Brain and Muscles of Patients with Nonspecific Neck Pain Treated by Spinal Manipulation Therapy: A [<sup>18</sup>F]FDG PET Study

<div>Results of positron emission tomography analysis of cervical muscles (paired <svg height="8.02022pt" id="M21" style="vertical-align:-0.2063999pt" version="1.1" viewbox="-0.0498162 -7.81382 4.54925 8.02022" width="4.54925pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M324 430H196L233 583L223 592L145 529L120 430H54L29 396L31 388H111L56 126C33 15 54 -12 77 -12C137 -12 214 57 250 95L233 119C208 92 155 59 138 59C126 59 120 70 131 125L186 390L298 394L324 430Z" id="g113-117"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="341" vert-adv-y="341"></glyph.data></g></svg>-test). The error bars represent standard deviations. The results indicate a trend toward reduction of mean standardized uptake value (SUV) after SMT; however, the difference is not statistically significant. Trap., trapezius muscle; Splenius, splenius muscles; Lev. Scap., levator scapulae; Semispinalis, semispinalis muscles; C7-T1, between the seventh cervical spine and the first thoracic spine; C6-C7, between the sixth cervical spine and the seventh cervical spine.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4: Glucose Metabolic Changes in the Brain and Muscles of Patients with Nonspecific Neck Pain Treated by Spinal Manipulation Therapy: A [<sup>18</sup>F]FDG PET Study 

Figure 4 | Glucose Metabolic Changes in the Brain and Muscles of Patients with Nonspecific Neck Pain Treated by Spinal Manipulation Therapy: A [18F]FDG PET Study 