Antiaging and Anxiolytic Effects of Combinatory Formulas Based on Four Medicinal Herbs

Figure 1

Spatial memory impairment in D-galactose-induced aging mice. D-gal mice were given daily 150 mg/kg D-galactose by subcutaneous injection with or without daily oral coadministration of different combinatorial herbal formulas (120 mg/kg) for eight weeks prior to the Y-maze test. Decreased percentile entry into novel arm (a) or time spent in novel arm (b) compared with vehicle-treated group (Veh) represented spatial memory impairment. Data are expressed in mean ± SD. ^###() indicates significant difference between D-gal group and Veh group, whereas () or () indicates significant difference between herbal group and D-gal group, based on one-way ANOVA test followed by Newman-Keuls test.

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