Antiaging and Anxiolytic Effects of Combinatory Formulas Based on Four Medicinal Herbs

Figure 4

Anxiolytic effect of different combinations of B, Y, P, and A herbs. The performances of mice treated with saline vehicle (Veh), diazepam (DZ), and different single-herb or multiherb extracts were assessed with respect to anxiolytic effect using the elevated plus-maze test, where increased percentage time spent in open arms compared with Veh represented an anxiolytic effect. Data are expressed in mean ± SD of the percentage of time spent in open arms. (), (), or () indicates significant difference from Veh group based on one-way ANOVA test followed by Newman-Keuls test.