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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 4673289, 10 pages
https://doi.org/10.1155/2017/4673289
Research Article

The Proliferation Enhancing Effects of Salidroside on Schwann Cells In Vitro

Hui Liu,1,2,3 Peizhen Lv,1,4 Huayu Wu,5 Kun Zhang,1,2 Fuben Xu,6,7 Li Zheng,1,3 and Jinmin Zhao1,2,3

1Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
2Department of Orthopaedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
3Guangxi Collaborative Innovation Center for Biomedicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
4Department of Spine Surgery, The Third Affiliated Hospital of Guangxi Medical University, Nanning, China
5Department of Cell Biology & Genetics, School of Premedical Sciences, Guangxi Medical University, Nanning, China
6Department of Genetic Metabolism, Children’s Hospital, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning 530003, China
7Guangxi Center for Birth Defects Research and Prevention, Nanning 530003, China

Correspondence should be addressed to Li Zheng; nc.ude.umxg@ilgnehz and Jinmin Zhao; moc.621@nimnijoahz

Received 7 November 2016; Revised 2 April 2017; Accepted 10 April 2017; Published 7 June 2017

Academic Editor: G. K. Jayaprakasha

Copyright © 2017 Hui Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. R. Robinson, “Traumatic injury to peripheral nerves,” Muscle & Nerve, vol. 23, no. 6, pp. 863–873, 2000. View at Publisher · View at Google Scholar · View at Scopus
  2. G. R. D. Evans, “Peripheral nerve injury: a review and approach to tissue engineered constructs,” Anatomical Record, vol. 263, no. 4, pp. 396–404, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. C. E. Schmidt and J. B. Leach, “Neural tissue engineering: strategies for repair and regeneration,” Annual Review of Biomedical Engineering, vol. 5, pp. 293–347, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. A. M. Moore, R. Kasukurthi, C. K. Magill, F. H. Farhadi, G. H. Borschel, and S. E. Mackinnon, “Limitations of conduits in peripheral nerve repairs,” Hand, vol. 4, no. 2, pp. 180–186, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. M. D. Wood, S. W. P. Kemp, C. Weber, G. H. Borschel, and T. Gordon, “Outcome measures of peripheral nerve regeneration,” Annals of Anatomy, vol. 193, no. 4, pp. 321–333, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Yi, Y. Yuan, Q. Chen et al., “Regulation of Schwann cell proliferation and migration by MIR-1 targeting brain-derived neurotrophic factor after peripheral nerve injury,” Scientific Reports, vol. 6, Article ID 29121, 2016. View at Publisher · View at Google Scholar · View at Scopus
  7. J. E. Springer, X. Mu, L. W. Bergmann, and J. Q. Trojanowski, “Expression of GDNF mRNA in Rat and Human Nervous Tissue,” Experimental Neurology, vol. 127, no. 2, pp. 167–170, 1994. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Acheson, P. A. Barker, R. F. Alderson, F. D. Miller, and R. A. Murphy, “Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: inhibition by antibodies to NGF,” Neuron, vol. 7, no. 2, pp. 265–275, 1991. View at Publisher · View at Google Scholar · View at Scopus
  9. J.-L. Shen, Y.-S. Chen, J.-Y. Lin et al., “Neuron regeneration and proliferation effects of danshen and tanshinone IIA,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 378907, 9 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Oudega and X.-M. Xu, “Schwann cell transplantation for repair of the adult spinal cord,” Journal of Neurotrauma, vol. 23, no. 3-4, pp. 453–467, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. G. Mudó, H. Persson, T. Timmusk, H. Funakoshi, M. Bindoni, and N. Belluardo, “Increased expression of trkB and trkC messenger RNAS in the rat forebrain after focal mechanical injury,” Neuroscience, vol. 57, no. 4, pp. 901–912, 1993. View at Publisher · View at Google Scholar · View at Scopus
  12. A. D. Toews, C. Barrett, and P. Morell, “Monocyte chemoattractant protein 1 is responsible for macrophage recruitment following injury to sciatic nerve,” Journal of Neuroscience Research, vol. 53, no. 2, pp. 260–267, 1998. View at Publisher · View at Google Scholar · View at Scopus
  13. G. K. Tofaris, P. H. Patterson, K. R. Jessen, and R. Mirsky, “Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF,” Journal of Neuroscience, vol. 22, no. 15, pp. 6696–6703, 2002. View at Google Scholar · View at Scopus
  14. R. Haranaka, R. Hasegawa, S. Nakagawa, A. Sakurai, N. Satomi, and K. Haranaka, “Antitumor activity of combination therapy with traditional chinese medicine and ok432 or MMC,” Journal of Biological Response Modifiers, vol. 7, no. 1, pp. 77–90, 1988. View at Google Scholar · View at Scopus
  15. H.-B. Li, Y.-K. Ge, X.-X. Zheng, and L. Zhang, “Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase,” European Journal of Pharmacology, vol. 588, no. 2-3, pp. 165–169, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Wang, Y. Ding, J. Zhou, X. Sun, and S. Wang, “The in vitro and in vivo antiviral effects of salidroside from Rhodiola rosea L. against coxsackievirus B3,” Phytomedicine, vol. 16, no. 2-3, pp. 146–155, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. X. Hu, S. Lin, D. Yu, S. Qiu, X. Zhang, and R. Mei, “A preliminary study: the anti-proliferation effect of salidroside on different human cancer cell lines,” Cell Biology and Toxicology, vol. 26, no. 6, pp. 499–507, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Ouyang, Z. Gao, Z. Ren, D. Hong, H. Qiao, and Y. Chen, “Synergistic effects of rMSCs and salidroside on the experimental hepatic fibrosis,” Die Pharmazie, vol. 65, no. 8, pp. 607–613, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. E. W. Qian, D. T. Ge, and S.-K. Kong, “Salidroside promotes erythropoiesis and protects erythroblasts against oxidative stress by up-regulating glutathione peroxidase and thioredoxin,” Journal of Ethnopharmacology, vol. 133, no. 2, pp. 308–314, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. L. Zhang, H. Yu, Y. Sun et al., “Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells,” European Journal of Pharmacology, vol. 564, no. 1–3, pp. 18–25, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. X. Chen, J. Liu, X. Gu, and F. Ding, “Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats,” Brain Research, vol. 1238, pp. 189–198, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. Q.-Y. Li, H.-M. Wang, Z.-Q. Wang, J.-F. Ma, J.-Q. Ding, and S.-D. Chen, “Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells,” Neuroscience Letters, vol. 481, no. 3, pp. 154–158, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. Q.-S. Sheng, Z.-J. Wang, J. Zhang, and Y.-G. Zhang, “Salidroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats,” NeuroReport, vol. 24, no. 5, pp. 217–223, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. H. E. Olson, G. E. Rooney, L. Gross et al., “Neural stem cell- and schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord,” Tissue Engineering—Part A, vol. 15, no. 7, pp. 1797–1805, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. Y.-M. Chang, W.-H. Kuo, T.-Y. Lai et al., “RSC96 schwann cell proliferation and survival induced by dilong through PI3K/Akt signaling mediated by IGF-I,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 216148, 9 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. L. Zhang, H. Yu, X. Zhao et al., “Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells,” Neurochemistry International, vol. 57, no. 5, pp. 547–555, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. L. F. Barbisan, M. Miyamoto, C. Scolastici et al., “Influence of aqueous extract of Agaricus blazei on rat liver toxicity induced by different doses of diethylnitrosamine,” Journal of Ethnopharmacology, vol. 83, no. 1-2, pp. 25–32, 2002. View at Publisher · View at Google Scholar · View at Scopus
  28. X. Chen, A. Deng, T. Zhou, and F. Ding, “Pretreatment with 2-(4-Methoxyphenyl)ethyl-2-acetamido-2-deoxy-β-D- pyranoside attenuates cerebral ischemia/reperfusion-induced injury in vitro and in vivo,” PLoS ONE, vol. 9, no. 7, Article ID e100126, 2014. View at Publisher · View at Google Scholar · View at Scopus
  29. C. B. Tan, M. Gao, W. R. Xu, X. Y. Yang, X. M. Zhu, and G. H. Du, “Protective effects of salidroside on endothelial cell apoptosis induced by cobalt chloride,” Biological & Pharmaceutical Bulletin, vol. 32, no. 8, pp. 1359–1363, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. J. Zhang, A. Liu, R. Hou et al., “Salidroside protects cardiomyocyte against hypoxia-induced death: A HIF-1α-activated and VEGF-mediated pathway,” European Journal of Pharmacology, vol. 607, no. 1–3, pp. 6–14, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. B. Zhang, Y. Wang, H. Li et al., “Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer’s disease models,” Drug Design, Development and Therapy, vol. 10, pp. 1335–1343, 2016. View at Publisher · View at Google Scholar · View at Scopus
  32. S. A. Hoyng, F. De Winter, S. Gnavi et al., “A comparative morphological, electrophysiological and functional analysis of axon regeneration through peripheral nerve autografts genetically modified to overexpress BDNF, CNTF, GDNF, NGF, NT3 or VEGF,” Experimental Neurology, vol. 261, pp. 578–593, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. P. Menei, C. Montero-Menei, S. R. Whittemore, R. P. Bunge, and M. B. Bunge, “Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord,” European Journal of Neuroscience, vol. 10, no. 2, pp. 607–621, 1998. View at Publisher · View at Google Scholar · View at Scopus
  34. L. N. Pettingill, A. K. Wise, M. S. Geaney, and R. K. Shepherd, “Enhanced auditory neuron survival following cell-based bdnf treatment in the deaf guinea pig,” PLoS ONE, vol. 6, no. 4, Article ID e18733, 2011. View at Publisher · View at Google Scholar · View at Scopus
  35. L. Zhang, Z. Ma, G. M. Smith et al., “GDNF-enhanced axonal regeneration and myelination following spinal cord injury is mediated by primary effects on neurons,” GLIA, vol. 57, no. 11, pp. 1178–1191, 2009. View at Publisher · View at Google Scholar · View at Scopus
  36. B. Stankoff, M.-S. Aigrot, F. Noël, A. Wattilliaux, B. Zalc, and C. Lubetzki, “Ciliary neurotrophic factor (CNTF) enhances myelin formation: a novel role for CNTF and CNTF-related molecules,” The Journal of Neuroscience, vol. 22, no. 21, pp. 9221–9227, 2002. View at Google Scholar · View at Scopus
  37. K. K. Modi, M. Sendtner, and K. Pahan, “Up-regulation of ciliary neurotrophic factor in astrocytes by aspirin; Implications for remyelination in multiple sclerosis,” Journal of Biological Chemistry, vol. 288, no. 25, pp. 18533–18545, 2013. View at Publisher · View at Google Scholar · View at Scopus
  38. A. Kumar, H. K. Mishra, P. Dwivedi, and J. R. Subramaniam, “Secreted trophic factors of Human umbilical cord stromal cells induce differentiation and neurite extension through PI3K and independent of cAMP pathway,” Annals of Neurosciences, vol. 22, no. 2, pp. 97–106, 2015. View at Publisher · View at Google Scholar · View at Scopus
  39. X. Dong, X. Zhang, D. Li et al., “Protective effect of salidroside against high altitude hypoxia-induced brain injury in rats,” Chinese Journal of Cellular and Molecular Immunology, vol. 31, no. 10, pp. 1327–1331, 2015. View at Google Scholar
  40. S. A. Mandel, Y. Sagi, and T. Amit, “Rasagiline promotes regeneration of substantia nigra dopaminergic neurons in post-MPTP-induced parkinsonism via activation of tyrosine kinase receptor signaling pathway,” Neurochemical Research, vol. 32, no. 10, pp. 1694–1699, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. J. S. Day, E. O'Neill, C. Cawley et al., “Noradrenaline acting on astrocytic β2-adrenoceptors induces neurite outgrowth in primary cortical neurons,” Neuropharmacology, vol. 77, pp. 234–248, 2014. View at Publisher · View at Google Scholar · View at Scopus