Assessment of Toxicity and Beneficiary Effects of Garcinia pedunculata on the Hematological, Biochemical, and Histological Homeostasis in Rats
Table 3
Effects of G. pedunculata fruit extract on the hematological parameters of whole blood.
Hematological parameters
Control
G. pedunculata treatment group
250 mg/kg
500 mg/kg
1000 mg/kg
WBC (×/L)
5.32 ± 0.70
5.67 ± 1.16
5.71 ± 0.73
5.76 ± 1.70
Neutrophils (%)
34.55 ± 1.56
34.65 ± 6.77
36.87 ± 20.92
34.07 ± 9.92
Lymphocytes (%)
60.90 ± 5.63
61.05 ± 4.70
61.20 ± 21.12
61.8 ± 12.14
Monocytes (%)
1.27 ± 0.17
1.15 ± 0.12
1.15 ± 0.12
1.35 ± 0.31
Eosinophils (%)
1.17 ± 0.53
1.22 ± 0.58
1.05 ± 0.49
0.90 ± 0.21
RBC (×/L)
7.43 ± 0.69
7.83 ± 0.53
7.38 ± 0.90
7.48 ± 1.39
HGB (g/dL)
14.00 ± 2.32
15.10 ± 0.76
14.00 ± 1.57
14.07 ± 2.43
HCT (%)
41.65 ± 3.07
41.55 ± 1.98
40.85 ± 3.58
40.92 ± 0.83
MCV (fL)
52.72 ± 1.51
52.82 ± 2.59
52.00 ± 1.80
52.83 ± 0.89
MCH (pg)
18.92 ± 0.37
19.12 ± 0.38
19.25 ± 0.42
19.12 ± 0.45
MCHC (g/dL)
36.3 ± 0.63
36.92 ± 1.47
36.92 ± 0.38
36.20 ± 0.43
PLT (×/L)
877 ± 51.26
827 ± 53.67
875.75 ± 52.88
889.25 ± 69.19
RDW-SD (fL)
32.92 ± 3.03
32.60 ± 1.73
31.4 ± 1.34
32.37 ± 2.26
RDW-CV (%)
20.32 ± 2.88
20.65 ± 1.11
20.31 ± 1.42
20.52 ± 2.00
PDW (fL)
10.42 ± 0.32
10.07 ± 0.83
9.52 ± 0.35
9.90 ± 0.74
MPV (fL)
9.30 ± 0.18
9.05 ± 0.44
8.77 ± 0.26
8.95 ± 0.36
P-LCR (%)
19.62 ± 1.38
17.92 ± 3.83
15.37 ± 2.42
16.57 ± 2.71
PCT (%)
0.75 ± 0.12
0.74 ± 0.07
0.72 ± 0.18
0.76 ± 0.04
Results are expressed as the mean ± SD (). Here, HGB: hemoglobin, HCT: hematocrit, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin, MCHC: mean corpuscular hemoglobin concentration, PLT: platelets, RDW-SD: red cell distribution width-standard deviation, RDW-CV: red cell distribution width-coefficient of variation, PDW-CV: platelets distribution width, MPV: mean platelets volume, P-LCR: platelets larger cell ratio, and PCT: procalcitonin.
