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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 4694238, 8 pages
https://doi.org/10.1155/2017/4694238
Research Article

Response of Local Nitric Oxide Release to Manual Acupuncture and Electrical Heat in Humans: Effects of Reinforcement Methods

1Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center and Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Torrance, CA 90502, USA
2Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center and Department of Neurology, David Geffen School of Medicine, University of California at Los Angeles, Torrance, CA 90502, USA

Correspondence should be addressed to Sheng-Xing Ma; gro.demoibal@amxs

Received 9 April 2017; Accepted 24 May 2017; Published 22 June 2017

Academic Editor: Gioacchino Calapai

Copyright © 2017 Sheng-Xing Ma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study was to examine the influences of manual acupuncture (MA) and electrical heat corresponding to reinforcing methods on nitric oxide (NO) release over the skin regions in humans. A device with collecting solution was taped to the skin surface along pericardium (PC) or lung (LU) meridian. Acupuncture needles were gently inserted into PC 4 with reinforcing stimulation (low force/rate) for 20 minutes in the MA group. LU11 on the finger was heated (43-44°C) by electrical heat for 20 minutes. Biocapture was consecutively conducted for two 20-minute intervals during and after each treatment. Total nitrite and nitrate () in the collecting samples were quantified using chemiluminescence in blinded fashion. Baseline levels are higher and tended to be higher over PC and LU acupoints during the 1st biocapture. levels over PC regions were consistently increased by MA during both intervals. concentrations over LU acupoints were increased and tended to be increased by electrical heat in the 1st and 2nd biocapture. The results suggest that reinforcing MA and electrical heat induce NO released from the local skin regions with higher levels at acupoints, which improve local circulation and contribute to the beneficial effects of the therapies.