<i>trans</i>-Cinnamaldehyde Inhibits Microglial Activation and Improves Neuronal Survival against Neuroinflammation in BV2 Microglial Cells with Lipopolysaccharide Stimulation

<div><i>Effects of TCA on LPS-induced morphological alteration in BV2 cells</i>. Immunostaining of BV2 cells was performed by using anti-CD11b monoclonal antibody (red) in the presence of DAPI (blue). Staining was visualized under a fluorescence microscopy. Magnification is 20x and scale bar is 100 <i>μ</i>m. Insets show high-magnification representative BV2 cells. Control: untreated BV2 cells. Treatment condition: TCA: TCA (10 <i>μ</i>M) treatment alone. LPS: LPS (0.1 <i>μ</i>g/ml) stimulation alone. LPS + TCA: combined treatment of LPS (0.1 <i>μ</i>g/ml) and TCA (10 <i>μ</i>M).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: <i>trans</i>-Cinnamaldehyde Inhibits Microglial Activation and Improves Neuronal Survival against Neuroinflammation in BV2 Microglial Cells with Lipopolysaccharide Stimulation 

Figure 4 | trans-Cinnamaldehyde Inhibits Microglial Activation and Improves Neuronal Survival against Neuroinflammation in BV2 Microglial Cells with Lipopolysaccharide Stimulation 