Research Article

Extract of Fructus Cannabis Ameliorates Learning and Memory Impairment Induced by D-Galactose in an Aging Rats Model

Figure 5

Effect of EFC on memory impairment induced by D-gal administration ( for each group). The Morris water maze test was carried out to access the spatial learning and memory ability of rats. (a) Latencies to find a hidden platform in the water maze during the 5 training days. (b) Mean distance to reach the hidden platform during the 5 training days. (c) Time spent in the target quadrant where the platform was located during training days in the probe test. (d) Numbers of crossings of the exact location of the previous platform during the probe test. (e) The representative traces during the probe test. The results are presented as mean ± SE (). as compared to the normal control group. as compared to the D-gal model group. Statistical differences between groups were analyzed by one-way analysis of variance (ANOVA) followed by Dunnett’s test.
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