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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 4847869, 7 pages
Research Article

Musical Auditory Stimulation Influences Heart Rate Autonomic Responses to Endodontic Treatment

1Laboratório de Delineamento de Estudos e Escrita Científica, Faculdade de Medicina do ABC, Santo André, SP, Brazil
2Faculdade de Juazeiro do Norte, Juazeiro do Norte, CE, Brazil
3Centro de Estudos do Sistema Nervoso Autônomo (CESNA), Departamento de Fonoaudiologia, Faculdade de Filosofia e Ciências, UNESP, Marília, SP, Brazil
4Cardiorespiratory Research Group, Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, UK
5Disciplina de Ginecologia do Departamento de Obstetrícia e Ginecologia, FMUSP, São Paulo, SP, Brazil

Correspondence should be addressed to Milana Drumond Ramos Santana; moc.liamtoh@dnomurdlim

Received 11 July 2016; Revised 20 October 2016; Accepted 17 November 2016; Published 15 January 2017

Academic Editor: Jeng-Ren Duann

Copyright © 2017 Milana Drumond Ramos Santana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We aimed to evaluate the acute effect of musical auditory stimulation on heart rate autonomic regulation during endodontic treatment. The study included 50 subjects from either gender between 18 and 40 years old, diagnosed with irreversible pulpitis or pulp necrosis of the upper front teeth and endodontic treatment indication. HRV was recorded 10 minutes before (T1), during (T2), and immediately (T3 and T4) after endodontic treatment. The volunteers were randomly divided into two equal groups: exposed to music (during T2, T3, and T4) or not. We found no difference regarding salivary cortisol and anxiety score. In the group with musical stimulation heart rate decreased in T3 compared to T1 and mean RR interval increased in T2 and T3 compared to T1. SDNN and TINN indices decreased in T3 compared to T4, the RMSSD and SD1 increased in T4 compared to T1, the SD2 increased compared to T3, and LF (low frequency band) increased in T4 compared to T1 and T3. In the control group, only RMSSD and SD1 increased in T3 compared to T1. Musical auditory stimulation enhanced heart rate autonomic modulation during endodontic treatment.