Research Article

In Vivo and In Vitro Evaluation of Pharmacological Potentials of Secondary Bioactive Metabolites of Dalbergia candenatensis Leaves

Table 3

Analgesic activity of D. candenatensis on acetic acid-induced writhing in mice (mean ± SEM, ). See supplementary data associated with this table.

Animal groupsDoseMean writhing% writhing% inhibition of writhing

Control (1% v/v Tween-80 water)10 ml/kg19.60 ± 1.811000
Diclofenac sodium25 mg/kg4.60 ± 0.6823.4776.53
Extract I100 mg/kg15.00 ± 0.7176.5323.47
Extract II250 mg/kg11.60 ± 1.0859.1840.82
Extract III500 mg/kg8.4 ± 1.3342.8657.14

, significant compared to control.