Research Article
In Vivo and In Vitro Evaluation of Pharmacological Potentials of Secondary Bioactive Metabolites of Dalbergia candenatensis Leaves
Table 3
Analgesic activity of
D. candenatensis on acetic acid-induced writhing in mice (mean ± SEM,
). See
supplementary data associated with this table.
| Animal groups | Dose | Mean writhing | % writhing | % inhibition of writhing |
| Control (1% v/v Tween-80 water) | 10 ml/kg | 19.60 ± 1.81 | 100 | 0 | Diclofenac sodium | 25 mg/kg | 4.60 ± 0.68 | 23.47 | 76.53 | Extract I | 100 mg/kg | 15.00 ± 0.71 | 76.53 | 23.47 | Extract II | 250 mg/kg | 11.60 ± 1.08 | 59.18 | 40.82 | Extract III | 500 mg/kg | 8.4 ± 1.33 | 42.86 | 57.14 |
|
|
, significant compared to control.
|