Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway

Figure 2

Effect of Sal on cell death in MPP+-treated SH-SY5Y cells. SH-SY5Y cells were pretreated with 25–100 μM Sal for 24 h and then exposed to 500 μM MPP+ for an additional 24 h. At the end, cell death was determined using Annexin V/PI assay kit and analyzed by flow cytometry (a). Cells were also stained with Hoechst to observe the morphological changes of nuclei (b).

(a)

(b)