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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 5398542, 11 pages
https://doi.org/10.1155/2017/5398542
Research Article

Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway

1Research Center of Traditional Chinese Medicine, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China
2Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, 169 West Changle Road, Xi’an 710032, China
3Department of Chinese Medicine, Xijing Hospital, Fourth Military Medical University, 169 West Changle Road, Xi’an 710032, China

Correspondence should be addressed to Jianzong Chen; nc.ude.ummf@75nehczj and Jing Ma; nc.ude.ummf@amgnij

Received 26 April 2017; Accepted 25 July 2017; Published 28 September 2017

Academic Editor: Gunhyuk Park

Copyright © 2017 Leitao Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. M. de Lau and M. M. Breteler, “Epidemiology of Parkinson's disease,” The Lancet Neurology, vol. 5, no. 6, pp. 525–535, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Navarro, A. Boveris, M. J. Bandez et al., “Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies,” Free Radical Biology & Medicine, vol. 46, pp. 1574–1580, 2009. View at Google Scholar
  3. M. Nagao and H. Hayashi, “Mixed lineage kinase 2 and hippocalcin are localized in Lewy bodies of Parkinson's disease,” Journal of the Neurological Sciences, vol. 281, no. 1-2, pp. 51–54, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. A. J. Hughes, S. E. Daniel, Y. Ben-Shlomo, and A. J. Lees, “The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service,” Brain, vol. 125, no. 4, pp. 861–870, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. G. J. McBean, M. G. López, and F. K. Wallner, “Redox-based therapeutics in neurodegenerative disease,” British Journal of Pharmacology, vol. 174, no. 12, pp. 1750–1770, 2017. View at Publisher · View at Google Scholar
  6. S. Singh, T. Das, A. Ravindran et al., “Involvement of nitric oxide in neurodegeneration: A study on the experimental models of Parkinson's disease,” Redox Report, vol. 10, no. 2, pp. 103–109, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. W. Meissner, M. P. Hill, F. Tison, C. E. Gross, and E. Bezard, “Neuroprotective strategies for Parkinson's disease: Conceptual limits of animal models and clinical trials,” Trends in Pharmacological Sciences, vol. 25, no. 5, pp. 249–253, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Foltynie and J. Kahan, “Parkinson's disease: An update on pathogenesis and treatment,” Journal of Neurology, vol. 260, no. 5, pp. 1433–1440, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. A. M. Díaz Lanza, M. J. Abad Martínez, L. Fernández Matellano et al., “Lignan and phenylpropanoid glycosides from Phillyrea latifolia and their in vitro anti-inflammatory activity,” Planta Medica, vol. 67, no. 3, pp. 219–223, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. G. S. Kelly, “Rhodiola rosea: a possible plant adaptogen,” Alternative Medicine Review, vol. 6, no. 3, pp. 293–302, 2001. View at Google Scholar · View at Scopus
  11. A. Kucinskaite, V. Briedis, and A. Savickas, “Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine,” Medicina, vol. 40, no. 7, pp. 614–619, 2004. View at Google Scholar · View at Scopus
  12. Q.-S. Sheng, Z.-J. Wang, J. Zhang, and Y.-G. Zhang, “Salidroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats,” NeuroReport, vol. 24, no. 5, pp. 217–223, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. D. Yin, W. Yao, S. Chen, R. Hu, and X. Gao, “Salidroside, the main active compound of rhodiola plants, inhibits high glucose-induced mesangial cell proliferation,” Planta Medica, vol. 75, no. 11, pp. 1191–1195, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. X. Li, X. Ye, X. Li et al., “Salidroside protects against MPP+-induced apoptosis in PC12 cells by inhibiting the NO pathway,” Brain Research, vol. 1382, pp. 9–18, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Wang, H. He, L. Chen, W. Zhang, X. Zhang, and J. Chen, “Protective effects of salidroside in the MPTP/MPP+-induced model of parkinson's disease through ros-no-related mitochondrion pathway,” Molecular Neurobiology, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. F. Yue, S. Zeng, R. Tang, G. Tao, and P. Chan, “MPTP Induces Systemic Parkinsonism in Middle-Aged Cynomolgus Monkeys: Clinical Evolution and Outcomes,” Neuroscience Bulletin, vol. 33, no. 1, pp. 17–27, 2017. View at Publisher · View at Google Scholar · View at Scopus
  17. X. Niu, H. Huang, J. Zhang et al., “Deletion of autophagy-related gene 7 in dopaminergic neurons prevents their loss induced by MPTP,” Neuroscience, vol. 339, pp. 22–31, 2016. View at Publisher · View at Google Scholar
  18. M. S. Nielsen, A. N. Glud, A. Møller et al., “Continuous MPTP intoxication in the göttingen minipig results in chronic parkinsonian deficits,” Acta Neurobiologiae Experimentalis, vol. 76, no. 3, pp. 199–211, 2016. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Chiba, A. Trevor, and N. Castagnoli Jr., “Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase,” Biochemical and Biophysical Research Communications, vol. 120, no. 2, pp. 574–578, 1984. View at Publisher · View at Google Scholar · View at Scopus
  20. C. S. Lee, J. H. Han, Y. Y. Jang, J. H. Song, and E. S. Han, “Differential effect of catecholamines and MPP+ on membrane permeability in brain mitochondria and cell viability in PC12 cells,” Neurochemistry International, vol. 40, no. 4, pp. 361–369, 2002. View at Publisher · View at Google Scholar · View at Scopus
  21. Z. Xu, D. Cawthon, K. A. McCastlain et al., “Selective alterations of transcription factors in MPP+-induced neurotoxicity in PC12 cells,” NeuroToxicology, vol. 26, no. 4, pp. 729–737, 2005. View at Publisher · View at Google Scholar · View at Scopus
  22. J.-Y. Choi, C.-S. Park, D.-J. Kim et al., “Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate,” NeuroToxicology, vol. 23, no. 3, pp. 367–374, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Dehmer, J. Lindenau, S. Haid, J. Dichgans, and J. B. Schulz, “Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo,” Journal of Neurochemistry, vol. 74, no. 5, pp. 2213–2216, 2000. View at Google Scholar · View at Scopus
  24. M. Di Nottia, M. Masciullo, D. Verrigni et al., “DJ-1 modulates mitochondrial response to oxidative stress: Clues from a novel diagnosis of PARK7,” Clinical Genetics, 2016. View at Publisher · View at Google Scholar · View at Scopus
  25. Y. Saito, Y. Akazawa-Ogawa, A. Matsumura et al., “Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients,” Scientific Reports, vol. 6, Article ID 30793, 2016. View at Publisher · View at Google Scholar · View at Scopus
  26. D.-K. Kim, M. A. Beaven, J. M. Kulinski et al., “Regulation of reactive oxygen species and the antioxidant protein DJ-1 in mastocytosis,” PLoS ONE, vol. 11, no. 9, Article ID e0162831, 2016. View at Publisher · View at Google Scholar · View at Scopus
  27. Y. Kitamura, M. Inden, Y. Kimoto et al., “Effects of a DJ-1-binding compound on spatial learning and memory impairment in a mouse model of Alzheimer's disease,” Journal of Alzheimer's Disease, vol. 55, no. 1, pp. 67–72, 2016. View at Publisher · View at Google Scholar · View at Scopus
  28. L. A. Greene and A. S. Tischler, “Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor,” Proceedings of the National Academy of Sciences of the United States of America, vol. 73, no. 7, pp. 2424–2428, 1976. View at Publisher · View at Google Scholar · View at Scopus
  29. L. Zhang, W. Ding, H. Sun et al., “Salidroside protects PC12 cells from MPP+-induced apoptosis via activation of the PI3K/Akt pathway,” Food and Chemical Toxicology, vol. 50, no. 8, pp. 2591–2597, 2012. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Guo, E. Bezard, and B. Zhao, “Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway,” Free Radical Biology and Medicine, vol. 39, no. 5, pp. 682–695, 2005. View at Publisher · View at Google Scholar · View at Scopus
  31. C. J. Choong and H. Mochizuki, “Gene therapy targeting mitochondrial pathway in Parkinson's disease,” Journal of neural transmission, pp. 10–1007, 1996. View at Google Scholar
  32. M. Soll, O. Bar Am, A. Mahammed et al., “Neurorescue by a ROS Decomposition Catalyst,” ACS Chemical Neuroscience, vol. 7, no. 10, pp. 1374–1382, 2016. View at Publisher · View at Google Scholar · View at Scopus
  33. X. Wang and C. Hai, “Novel insights into redox system and the mechanism of redox regulation,” Molecular Biology Reports, vol. 43, no. 7, pp. 607–628, 2016. View at Publisher · View at Google Scholar · View at Scopus
  34. S. C. Lu, “Glutathione synthesis,” Biochimica et Biophysica Acta, vol. 1830, no. 5, pp. 3143–3153, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. Q. Zhou, B. Chen, X. Wang et al., “Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways,” Scientific Reports, vol. 6, Article ID 32206, 2016. View at Publisher · View at Google Scholar · View at Scopus
  36. M. Todorovic, S. A. Wood, and G. D. Mellick, “Nrf2: a modulator of Parkinson’s disease?” Journal of Neural Transmission, vol. 123, no. 6, pp. 611–619, 2016. View at Publisher · View at Google Scholar · View at Scopus
  37. M. Ahuja, N. A. Kaidery, L. Yang et al., “Distinct Nrf2 signaling mechanisms of fumaric acid esters and their role in neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-induced experimental parkinson’s-like disease,” Journal of Neuroscience, vol. 36, no. 23, pp. 6332–6351, 2016. View at Publisher · View at Google Scholar · View at Scopus
  38. C. A. Massaad, T. M. Washington, R. G. Pautler, and E. Klann, “Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease,” Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 32, pp. 13576–13581, 2009. View at Publisher · View at Google Scholar · View at Scopus
  39. A. Wajda, J. Łapczuk, M. Grabowska et al., “Nuclear factor E2-related factor-2 (Nrf2) expression and regulation in male reproductive tract,” Pharmacological Reports, vol. 68, no. 1, pp. 101–108, 2016. View at Publisher · View at Google Scholar · View at Scopus
  40. D. Guan, Y. Su, Y. Li et al., “Tetramethylpyrazine inhibits CoCl2-induced neurotoxicity through enhancement of Nrf2/GCLc/GSH and suppression of HIF1α/NOX2/ROS pathways,” Journal of Neurochemistry, vol. 134, no. 3, pp. 551–565, 2015. View at Publisher · View at Google Scholar · View at Scopus
  41. K. Bahmed, E. M. Messier, W. Zhou et al., “DJ-1 modulates nuclear erythroid 2-related factor-2-mediated protection in human primary alveolar type II cells in smokers,” American Journal of Respiratory Cell and Molecular Biology, vol. 55, no. 3, pp. 439–449, 2016. View at Publisher · View at Google Scholar · View at Scopus
  42. E. Vázquez-Mayorga, Á. G. Díaz-Sánchez, R. K. Dagda et al., “Novel Redox-dependent Esterase activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson’s disease,” International Journal of Molecular Sciences, vol. 17, no. 8, article no. 1346, 2016. View at Publisher · View at Google Scholar · View at Scopus
  43. Y. Tan, L. Wu, D. Li, X. Liu, J. Ding, and S. Chen, “Methylation status of DJ-1 in leukocyte DNA of Parkinson's disease patients,” Translational Neurodegeneration, vol. 5, no. 1, article no. 5, 2016. View at Publisher · View at Google Scholar · View at Scopus
  44. M. E. Díaz-Casado, E. Lima, J. A. García et al., “Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network,” Journal of Pineal Research, vol. 61, no. 1, pp. 96–107, 2016. View at Publisher · View at Google Scholar