Therapeutic Effects of Fermented Flax Seed Oil on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions

Figure 1

The mitigative effect of FFSO treatment for AD. (a) The skin damage as eczema was mitigated in AT. (b) The damage of intercellular space of stratum corneum, hyperplasia, and infiltration of lymphocytes were increased in AE but decreased in AT. (H&E satin, Bar size, 100 m). The p-ERK 1/2 positive reaction in the AT was decreased in stratum granulosum. (p-ERK 1/2 immunohistochemistry, Bar size, 100 m). The decrease of edema was shown in AT as compared with AE. (Masson’s trichrome stain, Bar size, 100 m). The distribution of capillary was decreased in AT as compared with AE (Phloxine-tartrazine stain, Bar size, 100 m). Abbreviations. EP: epidermis; DE: dermis; M/T: Masson’s trichrome stain; P/T: Phloxine-tartrazine stain; Ctrl, induced AD and given water; AE, induced AD and given water; AT, induced AD with FFSO treatment.

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