Beneficial Effects of Paeoniflorin Enriched Extract on Blood Pressure Variability and Target Organ Damage in Spontaneously Hypertensive Rats

Figure 10

Effect on histopathology of kidney and renal function after being intervened by paeoniflorin enriched extract (PG). (a) Representative photomicrograph of histopathologic observation for glomerulus by hematoxylin-and-eosin staining (H&E) (400). (b) Representative photomicrograph of histopathologic observation for glomerular afferent arteries by H&E (400). (c) Representative photomicrograph of histopathologic observation for kidney by Masson’s trichrome staining (40). (d) Representative photomicrograph of the COX-2 expression in kidney by immunohistochemistry (IHC) (400). (e) The renal function indexes of serum UA, BUN, and Cr. MG: model group; MP: metoprolol positive group; PG-H: PG high dose group (90 mg/kg); PG-L: PG low dose group (30 mg/kg). Data were mean ± SD (). versus MG.

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