Beneficial Effects of Paeoniflorin Enriched Extract on Blood Pressure Variability and Target Organ Damage in Spontaneously Hypertensive Rats

Figure 9

Effect on histopathology of heart after being intervened by paeoniflorin enriched extract (PG) for seven weeks. (a) Representative photomicrograph of histopathologic observation for heart by hematoxylin-and-eosin staining (H&E) (200). (b) Representative photomicrograph of histopathologic observation for heart by Masson’s trichrome staining (40). (c) Representative photomicrograph of the COX-2 expression in heart by immunohistochemistry (IHC) (400). MG: model group; MP: metoprolol positive group; PG-H: PG high dose group (90 mg/kg); PG-L: PG low dose group (30 mg/kg).

(a)

(b)

(c)