Research Article
Oral Administration of Tualang and Manuka Honeys Modulates Breast Cancer Progression in Sprague-Dawley Rats Model
Table 10
The immunohistochemical expression of antiapoptotic proteins in TH and MH treated tumours compared with the tumours of nontreated control; (a) +ive control for IHC analysis, (b) +ive control for study (group bearing breast cancer but received no honey treatment), (c) 1.0 g/kg TH, and (d) 1.0 g/kg MH. All specimens were examined at ×400 microscopic magnification and brown color showed antibody positivity. Arrows in plates (c) and (d) show lower expression of antiapoptotic proteins in treated tumours compared with the nontreated control. TNF-: tumour necrosis factor alpha, COX-2: cyclooxygenase-2, ESR1: estrogen receptor 1, Bcl-xL: B-cell lymphoma extra large, TH: Tualang honey, and MH: Manuka honey.
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