Research Article

Oral Administration of Tualang and Manuka Honeys Modulates Breast Cancer Progression in Sprague-Dawley Rats Model

Table 4

The gross morphology and histology of the breast tumours of rats in TH and MH treated groups compared with the nontreated positive control. The H & E stained sections examined under light microscopy at ×400 magnification. The majority of tumours in nontreated control group were of grade III with increased heterogeneous nuclei formation and mitotic activity (plate (a), arrow) compared with the tumours in TH and MH treatment groups which were of grade I and II (less aggressive) (B): (a) = +ive control, (b) = 1.0 g/kg TH, and (c) = 1.0 g/kg MH. TH: Tualang honey, MH: Manuka honey, and +ive control: group bearing breast cancer but received no honey treatment.

Study groups Group 1
+ive control
Group 2
1.0 g/kg TH
Group 3
1.0 g/kg MH

(A) The gross appearance of tumours
   (B) The histology of the breast cancer