Fuzheng Quxie Decoction Ameliorates Learning and Memory Impairment in SAMP8 Mice by Decreasing Tau Hyperphosphorylation

Figure 6

Western blot assessed the expression of p-PP2A (a), PP2Ac (b), NR2A (c), and NR2B (d). Compared to the control group, the expression of p-PP2A, PP2Ac, and NR2A was significantly decreased in hippocampal tissues of model group mice ( and 0.05 and , resp.). However, NR2B expression was not significantly different in model mice (). The expression of hippocampal p-PP2A and NR2A was significantly elevated in drug-treated mice ; NR2A was significantly elevated in memantine and high doses of FQD treated mice ( and 0.05, resp.), while PP2Ac and NR2B were not significantly different (). , .

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