Plasma Metabolomics Analysis Based on GC-MS in Infertile Males with Kidney-Yang Deficiency Syndrome
Table 2
The detailed results from the pathway analysis.
Pathway name
Hits/Total
Expected
Raw
Holm adjust
FDR
Impact
Alanine, aspartate, and glutamate metabolism
1/24
0.059826
0.058413
2.8402
1
0.52408
0.17664
Arginine and proline metabolism
2/77
0.19194
0.01394
4.273
1
0.2788
0.16538
Lysine degradation
1/47
0.11716
0.1117
2.192
1
0.55848
0.14675
Phenylalanine metabolism
1/45
0.11217
0.10717
2.2334
1
0.55848
0.11906
Aminoacyl-tRNA biosynthesis
4/75
0.18695
11.293
0.000997
0.000997
0.11268
D-Glutamine and D-glutamate metabolism
1/11
0.02742
0.027137
3.6069
1
0.31013
0.1123
Lysine biosynthesis
1/32
0.079767
0.07724
2.5608
1
0.55848
0.09993
Valine, leucine, and isoleucine biosynthesis
1/27
0.067304
0.06551
2.7255
1
0.52408
0.01325
Glutathione metabolism
2/38
0.094724
0.003499
5.6554
0.2764
0.098232
0.01095
Phenylalanine, tyrosine, and tryptophan biosynthesis
1/27
0.067304
0.06551
2.7255
1
0.52408
0.00062
Histidine metabolism
1/44
0.10968
0.10489
2.2548
1
0.55848
0.00051
Nitrogen metabolism
2/39
0.097216
0.003684
5.6038
0.28733
0.098232
0
D-Arginine and D-ornithine metabolism
1/8
0.019942
0.019797
3.9222
1
0.31013
0
Biotin metabolism
1/11
0.02742
0.027137
3.6069
1
0.31013
0
Valine, leucine, and isoleucine degradation
1/40
0.099709
0.095753
2.346
1
0.55848
0
Butanoate metabolism
1/40
0.099709
0.095753
2.346
1
0.55848
0
Porphyrin and chlorophyll metabolism
1/104
0.25924
0.23302
1.4566
1
1
0
In the table, the “Total” is the total number of compounds in the pathway, the “Hits” is the actually matched number from the use uploaded data, the “Raw ” is the original value calculated from the enrichment analysis, the “Holm ” is the value adjusted by Holm-Bonferroni method, the “FDR ” is the value adjusted using False Discovery Rate, and the “Impact” is the pathway impact value calculated from pathway topology analysis.
