Research Article

Antinociceptive Activities of the Methanolic Extract of the Stem Bark of Boswellia dalzielii Hutch. (Burseraceae) in Rats Are NO/cGMP/ATP-Sensitive-K+ Channel Activation Dependent

Table 2

Influence of BDME on blood parameters after vincristine-induced neuropathic pain in rats.

Dose
(mg/kg)
Haemoglobin
(g/dl)
RBC
(million/µl)
Hematocrit
(%)
WBC
(109/L)
Platelet count
(109/L)

Normal control-12.45 ± 0.257.06 ± 0.1940.38 ± 1.117.58 ± 0.28831.75 ± 34.48
Vincristine + vehicle-7.15 ± 0.393.90 ± 0.1925.93 ± 1.031.68 ± 0.14481.25 ± 26.80
Vincristine + Morphine511.60 ± 0.356.05 ± 0.5235.10 ± 1.279.00 ± 0.521074.00 ± 15.01
Vincristine + BDME50012.65 ± 0.556.87 ± 0.1439.68 ± 1.168.13 ± 0.491001.00 ± 58.87

RBC: red blood cell; WBC: white blood cell; Hb: haemoglobin. Each value represents the mean ± ESM for six animals and analyzed by two-way ANOVA followed by Tukey post hoc test. ; ; statistically significant compared to normal control. statistically significant compared to vincristine and vehicle. .