Research Article

Ping-Chong-Jiang-Ni Formula Induces Apoptosis and Inhibits Proliferation of Human Ectopic Endometrial Stromal Cells in Endometriosis via the Activation of JNK Signaling Pathway

Figure 2

PCJNF suppressed cell proliferation in a concentration-dependent manner in EESCs. EESCs were exposed to different concentration of PCJNF-containing serum (5%, 10%, 20%, and 40%) for 0, 24, 48, 72, 96, and 120 h, respectively. The cell viability was assessed by CCK8 assay. Compared with the CONT group, PCJNF-containing serum suppressed cell proliferation in a concentration-dependent manner: 5% and 10% PCJNF-containing serum had low or medium suppressive effects on cell proliferation, while 20% and 40% PCJNF-containing serum resulted in significantly suppressed proliferation in EESCs. The experiment was performed in triplicate. CONT: EESCs cultured with complete medium. Data are presented as means ± SD of three independent tests.