Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research

Figure 1

Standard acupuncture acupoint locations in mouse and rat. GV26 is located at the junction of the upper and middle third of the philtrum. GV20 is located on the midline between the top of the ears. GV14 is located below the spinous process of the seventh vertebrae at the approximate level of the shoulders. BL23 is located on the posterior midline at the level of the lower border of the spinous process of the second lumbar vertebra. HT7 is located on the wrist at the ulnar end of the transverse crease of the wrist, in the depression on the radial side of the tendon musculus flexor carpi ulnaris. ST36 is located below the lower border of the patella, one finger width lateral from the anterior border of the tibia. SP6 is located on the inside of the leg just above the ankle. EX-HN3 is located on the anterior midline, between the eyes. Anatomical locations of the stimulated acupuncture points in mice and rats were equivalent to the acupoints in humans [11, 12]. The location of EX-HN3 was determined in accordance with the National Acupuncture Society for Experimental Research “Laboratory Animal Acupuncture Atlas.”