Sinomenine Hydrochloride Attenuates Renal Fibrosis by Inhibiting Excessive Autophagy Induced by Adriamycin: An Experimental Study

Figure 3

Telmisartan and SIN-HCl ameliorated the renal pathological changes in adriamycin-induced rats. Proliferative mesangial cells, increased ECM, thickened glomerular basement membrane, and disorderly arranged renal tubular cells were showed in the model group. Compared with model group, telmisartan and SIN-HCl ameliorated the renal pathological changes in adriamycin-induced rats.