Evidence-Based Complementary and Alternative Medicine / 2017 / Article / Fig 1

Research Article

Restructuring Reward Mechanisms in Nicotine Addiction: A Pilot fMRI Study of Mindfulness-Oriented Recovery Enhancement for Cigarette Smokers

Figure 1

fMRI contrast of the group × time interaction on positive ER-BOLD response. A significant group (MORE, control) × time (Pre, Post) interaction was found in left ventral striatum (VS: −9, 14, −12; = 12.4, = 2.13) and right vmPFC (9, 26, −16; ’s() = 19.4, = 2.66, = 1648) ( < 0.05, α = .05, Monte Carlo). Parameter estimates from the model indicate a relative increase in BOLD response from baseline to 8 weeks post-MORE relative to the control group, who evidenced a decrease in BOLD response.