Wu-Mei-Wan Reduces Insulin Resistance via Inhibition of NLRP3 Inflammasome Activation in HepG2 Cells
Effects of WMW on the secretion of proinflammatory cytokines in HepG2 cells. HepG2 cells were treated with serum without WMW (N) or medicated serum containing low (L), middle (M), or high (H) dose of WMW for 24 h. Then, cells were stimulated with 5 μM nigericin for 45 min, and the supernatants were collected and analyzed by ELISA for measurement of IL-1β (a), MCP-1α (b), and TNF-α (c) concentrations. , , and .
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