Evidence-Based Complementary and Alternative Medicine

Research Article

Preventive Effects of a Chinese Herbal Formula, Shengjiang Xiexin Decoction, on Irinotecan-Induced Delayed-Onset Diarrhea in Rats

Table 3

Comparison of the activity of intestinal caspase-3 and fecal β-glucuronidase in different groups.
GroupActivity of intestinal caspase-3 (U)Activity of fecal β-glucuronidase (U)
Before irinotecan administrationAfter irinotecan administration
Blank control group6
Model control group5
Low-dose SXD group6
Middle-dose SXD group6
High-dose SXD group5
Notes: one unit of enzyme activity is the amount of enzyme that will cleave 1 nmol of the colorimetric substrate per hour at 37°C under saturated substrate concentrations. The data were expressed as mean ± SD. , , compared with blank control group; , , compared with the model group.