Ficus hispida Bark Extract Prevents Nociception, Inflammation, and CNS Stimulation in Experimental Animal Model
Table 7
Effect of EFHB on histamine-induced oedema paw volume in Wistar rats.
Treatment
Dose (mg/kg)
Right hind paw volume (% inhibition)
1 h
2 h
3 h
4 h
5 h
Vehicle
10 (ml/kg)
1.15 ± 0.29
1.35 ± 0.26
1.46 ± 0.21
1.57 ± 0.21
1.68 ± 0.24
Indomethacin
10
0.58 ± 0.27 (49.39%
0.61 ± 0.18 (54.37%
0.62 ± 0.14 (57.42%
0.56 ± 0.11 (64.33%
0.51 ± 0.11 (69.64%
EFHB
100
0.82 ± 0.19 (28.10%
1.02 ± 0.13 (24.65%
0.98 ± 0.16 (32.97%
1.03 ± 0.18 (34.39%
1.07 ± 0.12 (36.31%
EFHB
200
0.80 ± 0.17 (29.84%
0.82 ± 0.15 (39.56%
0.88 ± 0.21 (39.84%
0.91 ± 0.15 (42.03%
0.90 ± 0.16 (46.43%
EFHB
400
0.60 ± 0.14 (47.99%
0.68 ± 0.17 (49.63%
0.69 ± 0.15 (52.74%
0.68 ± 0.21 (56.68%
0.67 ± 0.13 (60.12%
Here, each value is presented as the mean ± SEM . EFHB = ethanol extract of Ficus hispida. Indicating compared with control group (Dunnett’s test). Indicating compared with control group (Dunnett’s test).
