Research Article
Poly-ε-Caprolactone Microsphere Polymers Containing Usnic Acid: Acute Toxicity and Anti-Inflammatory Activity
Table 2
Usnic acid (UA) and encapsulated usnic acid (UA-micro) effects over Swiss mice physiological parameters (n = 6 animals/group).
| | Groups | Dose/p.o.
mg/kg | Number of
deaths | Food consumption (g/day) | Water consumption
(mL/day) | Body weight (g) | | Early | End |
| | Control | | 0/6 | 25.11 ± 2.3 | 45.8 ± 1.3 | 32.6 ± 2.77 | 33.0 ± 3.2 | | UA-micro | 2000 | 0/6 | 25.52 ± 2.2 | 46.4 ± 2.1 | 30.3 ± 3.02 | 32.3 ± 1.2 | | UA | 2000 | 6/6 | — | — | 29.7 ± 1.34 | — | | UA | 300 | 0/6 | 20.61 ± 2.4 | 44.4 ± 1.2 | 28.9 ± 1.27 | 30.3 ± 1.0 | | UA | 50 | 0/6 | 23.75 ± 2.5 | 46.6 ± 3.1 | 30.6 ± 0.34 | 32.8 ± 1.84 |
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and when compared with control group.
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