Research Article

The Protective Effect of Lavender Essential Oil and Its Main Component Linalool against the Cognitive Deficits Induced by D-Galactose and Aluminum Trichloride in Mice

Table 2

Effects of LO and LI on the activities of SOD, GPX, and AChE and the content of MDA in the hippocampus and cortex of D-gal and AlCl3 treated mice. Values are expressed as mean ± SEM (–12 in each group). , compared with control group, and compared with AD group.

GroupsSODGPXMDAAChE

ControlHip201.64 ± 16.24129.42 ± 8.3979.20 ± 6.076.81 ± 0.26
Cort308.21 ± 45.21181.14 ± 9.3991.85 ± 1.937.33 ± 0.45
ModelHip161.98 ± 98.86 ± 9.54#100.40 ± 6.05#9.42 ± 0.32##
Cort204.65 ± 127.44 ± 111.54 ± 5.649.21 ±
LO-50 mg/kgHip173.67 ± 29.06114.88 ± 12.1391.82 ± 7.709.06 ± 1.03
Cort228.07 ± 36.26136.03 ± 19.86105.02 ± 3.668.75 ± 0.23
LO-100 mg/kgHip190.99 ± 127.87 ± 82.67 ± 8.06 ± 0.20
Cort292.86 ± 166.97 ± 6.5498.33 ± 7.307.53 ±
LI-50 mg/kgHip182.94 ± 11.76109.61 ± 4.4492.47 ± 4.778.85 ± 0.24
Cort270.18 ± 40.31147.65 ± 14.32101.35 ± 8.658.95 ± 0.62
LI-100 mg/kgHip197.27 ± 128.90 ± 80.47 ± 7.96 ±
Cort302.52 ± 177.34 ± 93.67 ± 15.057.43 ±