A Chinese Herbal Formula, Gengnianchun, Ameliorates β-Amyloid Peptide Toxicity in a Caenorhabditis elegans Model of Alzheimer’s Disease

Figure 6

GNC promoted DAF-16 nuclear localization. (a) Representative images for the localization phenotype of DAF-16::GFP in TJ356 adults. Worms were classified into the categories of “cytosolic” (A), “intermediate” (B), and “nuclear” (C) according to their localization phenotypes. (b) Quantization of the distribution of cytosolic, intermediate, and nuclear DAF-16::GFP under oxidative stress conditions. The subcellular distribution of DAF-16 was examined in approximately 20 animals per condition by fluorescence microscopy. The phenotype results were presented in ratio to the whole population at each treatment condition.

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