Research Article
Components of Goutengsan in Rat Plasma by Microdialysis Sampling and Its Protection on Aβ1–42-Induced PC12 Cells Injury
Figure 1
(a) Cell viability of PC12 cells treated with different concentrations of Aβ1–42 (A) and Goutengsan extract (B). (b) The effect of Goutengsan on the apoptosis in Aβ1–42-induced PC12 cells by annexin V-FITc/PI double-staining analysis. (A) Control group; (B) model group; (C) positive control group (5 × 10−6 mol/L Nimodipine); (D) high dose of Goutengsan group (2 × 10−4 g/mL); (E) medium dose of Goutengsan group (1 × 10−4 g/mL); (F) low dose of Goutengsan group (2 × 10−5 g/mL). (c) Quantitative data of Aβ1–42-induced PC12 cells exposed to Goutengsan for 24 hours. The data were shown as mean ± SD, . , control group versus model group. , Nimodipine group versus model group, and Goutengsan group versus model group.
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