Huanglian-Jie-Du-Tang Extract Ameliorates Depression-Like Behaviors through BDNF-TrkB-CREB Pathway in Rats with Chronic Unpredictable Stress

Figure 10

Effect of HJDT on proinflammatory and anti-inflammatory cytokines mRNA in the hippocampus after the CUS. The effects of HJDT on the iNOS mRNA (a), IL-6/IL-10 mRNA ratio (b), IL-1β mRNA (c), and TNF-α mRNA (d) in the hippocampus. and relative to the normal control group; relative to the CUS depression group. N: normal control group; D: CUS depression group; P: paroxetine group; HJDT 2: HJDT 2 g/kg group; HJDT 4: HJDT 4 g/kg group; HJDT 8: HJDT 8 g/kg group.

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