Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 7924148, 4 pages
https://doi.org/10.1155/2017/7924148
Research Article

Optimal Dose of Epidural Dexmedetomidine Added to Ropivacaine for Epidural Labor Analgesia: A Pilot Study

Department of Anesthesiology, Affiliated Women and Children’s Hospital of Jiaxing University, Jiaxing, China

Correspondence should be addressed to Ren Ming; moc.qq@4053770191

Received 30 December 2016; Accepted 27 April 2017; Published 1 June 2017

Academic Editor: Armando Zarrelli

Copyright © 2017 Zhang Wangping and Ren Ming. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. M. El-Hennawy, A. M. Abd-Elwahab, A. M. Abd-Elmaksoud, H. S. El-Ozairy, and S. R. Boulis, “Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children,” British Journal of Anaesthesia, vol. 103, no. 2, pp. 268–274, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Yoshitomi, A. Kohjitani, S. Maeda, H. Higuchi, M. Shimada, and T. Miyawaki, “Dexmedetomidine enhances the local anesthetic action of lidocaine via an α-2a adrenoceptor,” Anesthesia and Analgesia, vol. 107, no. 1, pp. 96–101, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. R. D'Angelo, L. S. Dean, G. C. Meister, and K. E. Nelson, “Neostigmine combined with bupivacaine, clonidine, and sufentanil for spinal labor analgesia,” Anesthesia and Analgesia, vol. 93, no. 6, pp. 1560–1564, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. A. T.-H. Sia, “Optimal dose of intrathecal clonidine added to sufentanil plus bupivacaine for labour analgesia,” Canadian Journal of Anesthesia, vol. 47, no. 9, pp. 875–880, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. J. C. Eisenach, M. De Kock, and W. Klimscha, “α2–Adrenergic agonists for regional anesthesia: a clinical review of clonidine (1984–1995),” Anesthesiology, vol. 85, no. 3, pp. 655–674, 1996. View at Publisher · View at Google Scholar · View at Scopus
  6. S. J. S. Bajwa, V. Arora, J. Kaur, A. Singh, and S. S. Parmar, “Comparative evaluation of dexmedetomidine and fentanyl for epidural analgesia in lower limb orthopedic surgeries,” Saudi Journal of Anaesthesia, vol. 5, no. 4, pp. 365–370, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. N. Sethi, D. Pant, A. Dutta, A. Koul, J. Sood, and P. T. Chugh, “Comparison of caudal epidural block and ultrasonography-guided transversus abdominis plane block for pain relief in children undergoing lower abdominal surgery,” Journal of Clinical Anesthesia, vol. 33, pp. 322–329, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. S. R. Arain, R. M. Ruehlow, T. D. Uhrich, and T. J. Ebert, “The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery,” Anesthesia and Analgesia, vol. 98, no. 1, pp. 153–158, 2004. View at Google Scholar · View at Scopus
  9. A. M. Vieira, T. B. Schnaider, A. C. Brandão, F. A. Pereira, E. D. Costa, and C. E. P. Fonseca, “Epidural clonidine or dexmedetomidine for post–cholecystectomy analgesia and sedation,” Revista Brasileira de Anestesiologia, vol. 54, no. 4, pp. 473–478, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. T. B. Schnaider, A. M. Vieira, A. C. Aguiar Brandão, and M. V. Tonante Lobo, “Intraoperative analgesic effect of epidural ketamine, clonidine or dexmedetomidine for upper abdominal surgery,” Revista Brasileira de Anestesiologia, vol. 55, no. 5, pp. 525–531, 2005. View at Google Scholar · View at Scopus
  11. M. A. Ramsay, T. M. Savege, B. R. Simpson, and R. Goodwin, “Controlled sedation with alphaxalone–alphadolone,” British Medical Journal, vol. 2, no. 920, pp. 656–659, 1974. View at Publisher · View at Google Scholar · View at Scopus
  12. B. Civantos Calzada and A. A. de Artiñano, “Alpha–adrenoceptor subtypes,” Pharmacological Research, vol. 44, no. 3, pp. 195–208, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. C. N. Dinesh, N. A. Sai Tej, B. Yatish, V. S. Pujari, R. M. Mohan Kumar, and C. V. R. Mohan, “Effects of intravenous dexmedetomidine on hyperbaric bupivacaine spinal anesthesia: a randomized study,” Saudi Journal of Anaesthesia, vol. 8, no. 2, pp. 202–208, 2014. View at Publisher · View at Google Scholar · View at Scopus
  14. A. T. Sia, K. Kwek, and G. S. Yeo, “The in vitro effects of clonidine and dexmedetomidine on human myometrium,” International Journal of Obstetric Anesthesia, vol. 14, no. 2, pp. 104–107, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Konakci, T. Adanir, G. Yilmaz, and T. Rezanko, “The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route,” European Journal of Anaesthesiology, vol. 25, no. 5, pp. 403–409, 2008. View at Publisher · View at Google Scholar · View at Scopus