Pharmacological Effect of Caulophyllum robustum on Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-κB, and Proinflammatory Cytokines In Vivo and In Vitro

Figure 6

Analysis of immunohistochemistry of the right hind limbs. After the intervention, mice were sacrificed, and, then, the joints were subjected to immunohistochemistry for NF-κB p65. (a) NF-κB p65; (b) IOD of NF-κB p65. The data are presented as the mean ± SD with mice per group. Data were analyzed by two-way ANOVA, Student-Newman-Keuls test as post hoc test ( and , compared with the vehicle group. , compared with the MTX group. and , compared with the Tri group). HE stain, scale bars = 400 nd.

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