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Evidence-Based Complementary and Alternative Medicine
Volume 2017 (2017), Article ID 8256278, 9 pages
https://doi.org/10.1155/2017/8256278
Research Article

Renoprotective Effects of Total Glucosides from Paeony against Nephrotoxicity Induced by Total Alkaloids from Semen Strychni

1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
2School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China

Correspondence should be addressed to Xiaohui Chen; moc.liamtoh@uhpys_hxc

Received 1 May 2017; Revised 18 July 2017; Accepted 2 August 2017; Published 22 October 2017

Academic Editor: Caigan Du

Copyright © 2017 Mingming Lv et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Chinese Pharmacopoeia Commission, Pharmacopoeia of the People's Republic of China, vol. 1, China Medical Science Press, 2010.
  2. S. Saraswati, A. A. Alhaider, and S. S. Agrawal, “Anticarcinogenic effect of brucine in diethylnitrosamine initiated and phenobarbital-promoted hepatocarcinogenesis in rats,” Chemico-Biological Interactions, vol. 206, no. 2, pp. 214–221, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Li, M. Zhang, P. Hou et al., “Identification of the toxic components in SemenStrychni and their metabolites in rat serum by high performance liquid chromatography coupled with a Q Exactive high-resolution benchtop quadrupole Orbitrap mass spectrometer,” RSC Advances, vol. 95, no. 5, pp. 77689–77698, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. B. C. Cai, H. Wu, X. W. Yang et al., “Analysis of Spectral Data for 13CNMR of Sixteen Strychnos Alkaloids,” Acta Pharmaceutica Sinica, vol. 29, 48 pages, 1994. View at Google Scholar
  5. G. Yang, Y. Pan, L. Liu, and Y. Jiang, “Simultaneous determination of strychnine, brucine, strychnine N-oxide and brucine N-oxide in crude and fermented nux vomica by CZE with ephedrine hydrochloride as an internal standard,” Chromatographia, vol. 73, no. 11-12, pp. 1223–1228, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. J.-X. Tian, C. Peng, L. Xu, Y. Tian, and Z.-J. Zhang, “In vitro metabolism study of Strychnos alkaloids using high-performance liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry,” Biomedical Chromatography, vol. 27, no. 6, pp. 775–783, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. X.-K. Deng, W. Yin, W.-D. Li et al., “The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism,” Journal of Ethnopharmacology, vol. 106, no. 2, pp. 179–186, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. J. A. Perper, “Fatal strychnine poisoning—A case report and review of the literature,” Journal of Forensic Sciences, vol. 30, no. 4, pp. 1248–1255, 1985. View at Google Scholar · View at Scopus
  9. G. Philippe, L. Angenot, M. Tits, and M. Frédérich, “About the toxicity of some Strychnos species and their alkaloids,” Toxicon, vol. 44, no. 4, pp. 405–416, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. D. M. Wood, E. Webster, D. Martinez, P. I. Dargan, and A. L. Jones, “Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data,” Critical Care, vol. 6, no. 5, pp. 456–459, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Duverneuil, G. L. De La Grandmaison, P. De Mazancourt, and J.-C. Alvarez, “Liquid chromatography/photodiode array detection for determination of strychnine in blood: A fatal case report,” Forensic Science International, vol. 141, no. 1, pp. 17–21, 2004. View at Publisher · View at Google Scholar · View at Scopus
  12. K. Wang, Y.-G. Wu, J. Su, J.-J. Zhang, P. Zhang, and X.-M. Qi, “Total glucosides of paeony regulates JAK2/STAT3 activation and macrophage proliferation in diabetic rat kidneys,” American Journal of Chinese Medicine, vol. 40, no. 3, pp. 521–536, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Gu, X. Wang, Z. Liu et al., “A study of Semen Strychni-induced renal injury and herb-herb interaction of Radix Glycyrrhizae extract and/or Rhizoma Ligustici extract on the comparative toxicokinetics of strychnine and brucine in rats,” Food and Chemical Toxicology, vol. 68, pp. 226–233, 2014. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Tang, Y. Liu, and X. Liang, “Effect of compatibility of nux vomica and radix paeoniae alba on anti-inflammatory and immune of adjuvant arthritis rats and mechanism analysis,” Journal Tradition Chinese Medicine, vol. 33, no. 8, pp. 10106–10140, 2014. View at Google Scholar
  15. Y. Liu, X. Liang, and Y. Tang, “Effect of compatibility of nux vomica and radix paeoniae alba on LD50 and analgesic effect of mice,” Journal Tradition Chinese Medicine, vol. 33, no. 8, pp. 660–662, 2014. View at Google Scholar
  16. D.-Y. He and S.-M. Dai, “Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., a traditional Chinese herbal medicine,” Frontiers in Pharmacology, vol. 2, article 10, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. C. Wang, J. Yuan, H.-X. Wu et al., “Total glucosides of paeony inhibit the inflammatory responses of mice with allergic contact dermatitis by restoring the balanced secretion of pro-/anti-inflammatory cytokines,” International Immunopharmacology, vol. 24, no. 2, pp. 325–334, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Su, P. Zhang, J.-J. Zhang, X.-M. Qi, Y.-G. Wu, and J.-J. Shen, “Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats,” Phytomedicine, vol. 17, no. 3-4, pp. 254–260, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. X.-X. Xu, X.-M. Qi, W. Zhang et al., “Effects of total glucosides of paeony on immune regulatory toll-like receptors TLR2 and 4 in the kidney from diabetic rats,” Phytomedicine, vol. 21, no. 6, pp. 815–823, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. H. Wu, G. Chen, K. R. Wyburn et al., “TLR4 activation mediates kidney ischemia/reperfusion injury,” Journal of Clinical Investigation, vol. 117, no. 10, pp. 2847–2859, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. U. S. Food, “Drug Administration FDA, Guidance for Industry: Bioanalytical Method Validation,” in US Department of Health and Human, Services Food and Drug Administration, and Center for Drug Evaluation and Research, USA, 2001. View at Google Scholar
  22. Y. Zhang, Z. Liu, R. Zhang, P. Hou, K. Bi, and X. Chen, “Nephrotoxicity evaluation of a new cembrane diterpene from Euphorbiae pekinensis Radix with HEK 293T cells and the toxicokinetics study in rats using a sensitive and reliable UFLC-MS/MS,” Journal of Pharmaceutical and Biomedical Analysis, vol. 119, pp. 159–165, 2016. View at Publisher · View at Google Scholar · View at Scopus
  23. D. Galmarini, L. Tarenzi, and G. Cantaluppi, “Acute hepatic failure and renal damage. Experimental and clinical studies,” Panminerva, vol. 69, no. 27, pp. 1417–1426, 1978. View at Google Scholar
  24. A. Jamshidzadeh, R. Heidari, T. Golzar, and A. Derakhshanfar, “Effect of eisenia foetida extract against cisplatin-induced kidney injury in rats,” Journal of Dietary Supplements, vol. 13, no. 5, pp. 551–559, 2016. View at Publisher · View at Google Scholar · View at Scopus
  25. R. W. Schrier, W. Wang, B. Poole, and A. Mitra, “Acute renal failure: definitions, diagnosis, pathogenesis, and therapy,” Journal of Clinical Investigation, vol. 114, no. 1, pp. 5–14, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. S. G. Emeigh Hart, “Assessment of renal injury in vivo,” Journal of Pharmacological and Toxicological Methods, vol. 52, no. 1, pp. 30–45, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. C. Liu, Z. Cheng, Y. Wang, X. Dai, J. Zhang, and D. Xue, “Paeoniflorin exerts a nephroprotective effect on concanavalin A-induced damage through inhibition of macrophage infiltration,” Diagnostic Pathology, vol. 10, no. 1, article no. 120, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. Y. P. Zhu, “Toxicology of the Chinese herb mu tong (Aristolochia manshuriensis). What history tells us,” Adverse Drug React Toxicology Reviews, vol. 21, no. 4, pp. 171–177, 2002. View at Publisher · View at Google Scholar
  29. L. Liu, X.-P. Zhao, D.-F. Zhu, Y.-Y. Cheng, and H.-B. Qu, “Simultaneous LC-MS/MS determination of danshensu and paeoniflorin for permeability studies in Caco-2 intestinal absorption model,” Chemical Research in Chinese Universities, vol. 24, no. 4, pp. 420–426, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. C. W. Nogueira, L. P. Borges, and A. C. G. Souza, “Oral administration of diphenyl diselenide potentiates hepatotoxicity induced by carbon tetrachloride in rats,” Journal of Applied Toxicology, vol. 29, no. 2, pp. 156–164, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Mishima, Y. Tanimoto, Z. Oguri, and H. Yoshimura, “Metabolism of strychnine in vitro,” Drug Metabolism and Disposition, vol. 13, no. 6, pp. 716–721, 1985. View at Google Scholar · View at Scopus
  32. L.-N. Gao, Y. Zhang, Y.-L. Cui, and O. M. Akinyi, “Comparison of paeoniflorin and albiflorin on human CYP3A4 and CYP2D6,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 470219, 7 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  33. Y. Wu, K. Ren, C. Liang et al., “Renoprotective effect of total glucosides of paeony (TGP) and its mechanism in experimental diabetes,” Journal of Pharmacological Sciences, vol. 109, no. 1, pp. 78–87, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. L. Velíšek, “Models of Chemically-Induced Acute Seizures,” Models of Seizures and Epilepsy, pp. 127–152, 2006. View at Publisher · View at Google Scholar · View at Scopus