Evidence-Based Complementary and Alternative Medicine / 2017 / Article / Fig 2

Review Article

Brazilian Amazon Traditional Medicine and the Treatment of Difficult to Heal Leishmaniasis Wounds with Copaifera

Figure 2

Diterpenes found in copaiba oils. (A) Patagonic acid [R1 = H; R2= CH3; R3 = furanone]; (B) hardwickiic acid [R1 = COOH; R2 = H; R3 = furan]; (C) 15,16-epoxy-7β-acetoxy-3,13(16),14-clerodatriene-18-oic acid [R1 = H; R2 = H; R3 = furan]; (D) 7-hydroxyhardwickiic acid [R1 = OH; R2 = CH3 R3 = furan]; (E) clerodane-15,18-dioic acid [R1 = H; R2 = CH3; R3 = CH(CH3)CH2COOCH3]; (F) 3,13-clerodadiene-15-oic acid [R1 = COOH]; (G) colavenol [R1 = CH2OH, trans C1, C2]; (H) Cis-colavenol [R1 = CH2OH cis C1, C2]; (I) 13-clerodane-15,16-olideo-18-oic acid [R1 = furanone]; (J) clerodane-15,18-dioic acid [R1 = CH2(CH3)CH2CH2COOH]; (L) clorechinic acid [R1 = furan]; (M) copaiferolic acid [R1 = COOH; R2 = OH; R3 = H; R4 = H]; (N) copaiferic acid, [R1 = COOH; R2 = CH3; R3 = H; R4 = H]; (O) 8(17), 13-labdadiene-15-ol [R1 = CH2OH; R2 = CH3; R3 = H; R4 = H]; (P) 11-hydroxycopalic acid [R1 = COOH; R2 = CH3; R3 = OH; R4 = H]; (Q) ent-3-hydroxy-labda-8(17),13-diene-15-oic acid [R1 = COOH; R2 = CH3; R3 = H; R4 = OH]; (R) ent-agatic acid [R1 = COOH R2 = COOH R3 = H R4 = H]; (S) copalic acid [R1 = COOH; R2 = CH3; R3 = H; R4 = H]; (T) 11-acetoxy-copalic acid [R1 = COOH; R2 = CH3; R3 = CO2CH3; R4 = H]; (U) cativic acid; (V) ent-16(β)-cauranic-19-oic acid [R1 = CH3; R2 = H]; (X) ent-caura-16-ene-19-oic acid [R1 and R2 = CH2]; R1 and R2 need for two connections, one and one .