In Vivo Subacute Toxicity and Antidiabetic Effect of Aqueous Extract of Nigella sativa

Table 2

Urea, creatine, albumin, AST, ALT, and AP concentrations of mice.

Parameters	Control (water)	Concentrations of AqE.NS [g/kg]					Chi-square test
		2	6.4	21	33	60
Urea (mmol/L)	4.9	4.6	5.2	6.5	6.1	8.6	3.65	0.456
Creatine (μmol/L)	12	7	16	15	16	21	12.25	0.016
Albumin (g/L)	39.6	33.4	41.5	40.7	41.8	42.1	1.37	0.849
AST (U/L)	172.3	261.8	266.6	322.6	267.5	505.1	924.62	<0.001
ALT (U/L)	94.9	96.4	109.85	188.1	104.5	148.8	125.49	<0.001
Alkaline phosphatase (U/L)	110	93	105	93	114	87	10.44	0.034

: statistically significant.