Research Article
Study of the Hypoglycemic Activity of Derivatives of Isoflavones from Cicer arietinum L.
Table 4
Effects on glucose consumption of these derivatives in IR HepG2 cells (
).
| | Compounds | | EC50 | Standard deviation |
| | Metformin HCL | 3 | 3.332 | 1.212 | | Genistein | 3 | 22.212 | 1.112 | | Biochanin A | 3 | 380.234 | 3.652 | | Formononetin | 3 | 80.922 | 5.218 | | 1a | 3 | 300.221 | 13.221 | | 1b | 3 | 10.238 | 1.121 | | 1c | 3 | 401.588 | 14.322 | | 1d | 3 | 365.789 | 14.421 | | 2a | 3 | 123.981 | 13.921 | | 2b | 3 | 390.092 | 13.221 | | 2c | 3 | 452.289 | 15.682 | | 2d | 3 | 399.563 | 14.532 | | 3a | 3 | 482.229 | 25.685 | | 3b | 3 | 431.135 | 25.421 | | 3c | 3 | 23.678 | 1.331 | | 3d | 3 | 178.981 | 15.789 | | 3e | 3 | 300.982 | 24.001 | | 3f | 3 | 349.231 | 13.562 | | 3g | 3 | 372.221 | 13.862 | | 3h | 3 | 387.811 | 13.951 | | 4a | 3 | 392.381 | 14.562 | | 4b | 3 | 312.811 | 13.023 | | 4c | 3 | 342.873 | 13.465 | | 4d | 3 | 310.382 | 13.891 | | 4e | 3 | 24.981 | 1.223 | | 4f | 3 | 292.893 | 13.562 | | 4g | 3 | 273.445 | 12.119 | | 4h | 3 | 348.934 | 14.558 | | 4i | 3 | 356.378 | 13.214 | | 4h | 3 | 321.663 | 13.456 | | 5a | 3 | 456.897 | 24.721 | | 5b | 3 | 392.734 | 14.113 | | 5c | 3 | 321.665 | 14.112 | | 5d | 3 | 333.991 | 13.821 | | 6 | 3 | 13.934 | 1.223 |
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