Research Article
The Significant Pathways and Genes Underlying the Colon Cancer Treatment by the Traditional Chinese Medicine PHY906
Table 1
The overrepresented GO terms and pathways for differentially expressed genes.
| | Category | Term | Count | value |
| Up | BP | GO:0048545~response to steroid hormone stimulus | 6 | | GO:0007131~reciprocal meiotic recombination | 3 | | GO:0000279~M phase | 11 | | CC | GO:0015629~actin cytoskeleton | 10 | | GO:0005578~proteinaceous extracellular matrix | 12 | | GO:0044449~contractile fiber part | 6 | | MF | GO:0015082~di- and trivalent inorganic cation transmembrane transporter activity | 5 | | GO:0017076~purine nucleotide binding | 46 | | GO:0030674~protein binding, bridging | 4 | |
| Down | BP | GO:0032649~regulation of interferon-gamma production | 4 | | GO:0019439~aromatic compound catabolic process | 3 | | GO:0048535~lymph node development | 3 | | CC | GO:0000267~cell fraction | 18 | | GO:0005624~membrane fraction | 16 | | GO:0005626~insoluble fraction | 16 | | MF | GO:0005416~cation:amino acid symporter activity | 3 | | GO:0005506~iron ion binding | 11 | | GO:0015171~amino acid transmembrane transporter activity | 4 | | Pathway | mmu00380:tryptophan metabolism | 5 | |
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Up means upregulated genes, and down represents downregulated genes.
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