Resveratrol Attenuates Microglial Activation via SIRT1-SOCS1 Pathway

Figure 3

SIRT1-siRNA reversed resveratrol- (RSV-) induced effects on iNOS expression. The cells were divided into five groups and treated with different drugs as shown in the figure. After 24 h incubation, immunocytochemistry was used to observe the iNOS expression (red) in microglial cells, and the nuclei (blue) were counterstained with DAPI staining solution. Bar = 10 μm.