Urinary and Serum Metabolomics Analyses Uncover That Total Glucosides of Paeony Protect Liver against Acute Injury Potentially via Reprogramming of Multiple Metabolic Pathways

Figure 1

TGP protects hepatocytes from CCl₄-induced ALI. ((a) and (b)) Chemical structures of paeoniflorin and albiflorin, which are the two main compounds in the TGP extracted by our laboratory. (c) H&E staining of liver tissues in the control, CCl₄, and CCl₄ plus TGP groups. ((d) and (e)) Evaluation of ALT (d) and AST (e) levels in serum samples obtained from the indicated groups. All the data were statistically analyzed by Student’s -test. Different letters above the bars indicate statistically significant difference with .

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