Recuperating Lung Decoction Attenuates the Oxidative Stress State of Chronic Obstructive Pulmonary Disease by Inhibiting the MAPK/AP-1 Signal Pathway and Regulating γ-GCS

Figure 2

Influence of RLD on GSH, GSSG, 8-OHdG, and 4-HNE of COPD bronchoalveolar lavage fluid. (a) The GSH concentration of COPD rats was significantly lower than that of the normal group. The GSH concentration increased after NAC and RLD treatment. (b) The GSSG concentration of the COPD group was higher than that of the other groups. The GSSG level reduced after the NAC and RLD treatment. (c) The GSH/GSSG ratio after NAC and RLD treatment was higher than that of the COPD group. (d-e) The 8-OHdG and 4-HNE levels of the COPD group were higher than those of the normal group. The 8-OHdG and 4-HNE expression level reduced after NAC and RLD treatment. The data were expressed as mean ± SD. One-way ANOVA was adopted for statistical analysis. The Newman-Keuls was used for an intergroup comparison ( compared with the normal group, , , compared with the model group; ).

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